Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 14/20 | 0.54 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.54 |
| ▸ | GRAMD1A | Q96CP6 | 6/20 | 0.48 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | IL1B | P01584 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.47 |
| ▸ | BTK | Q06187 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26924761 | 1.00 | CRBN (0.54) | CRBNDDB1GRAMD1ATNFIL1B | |
| SCHEMBL31129461 | 0.96 | CRBN (0.56) | CRBNDDB1GRAMD1ATNFIL1B | |
| SCHEMBL31129396 | 0.92 | CRBN (0.53) | CRBNDDB1GRAMD1ATNFIL1B | |
| SCHEMBL23249910 | 0.89 | CRBN (0.51) | CRBNDDB1GRAMD1ATNFIL1B | |
| SCHEMBL29873939 | 0.89 | CRBN (0.51) | CRBNDDB1GRAMD1ATNFIL1B | |
| SCHEMBL20294709 | 0.89 | CRBN (0.59) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL30738833 | 0.89 | CRBN (0.54) | CRBNDDB1GRAMD1ATNFIL1B | |
| SCHEMBL24819464 | 0.89 | CRBN (0.54) | CRBNDDB1GRAMD1ATNFIL1B | |
| SCHEMBL30732167 | 0.87 | CRBN (0.54) | CRBNDDB1GRAMD1ATNFIL1B | |
| SCHEMBL26925221 | 0.87 | CRBN (0.54) | CRBNDDB1GRAMD1ATNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536650-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |