Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.57 |
| ▸ | DDB1 | Q16531 | 18/20 | 0.57 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.57 |
| ▸ | TNF | P01375 | 2/20 | 0.57 |
| ▸ | IL1B | P01584 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26925479 | 1.00 | CRBN (0.57) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL31129334 | 0.92 | DDB1 (0.57) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL31129482 | 0.88 | CRBN (0.53) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL24817809 | 0.88 | DDB1 (0.64) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL24269054 | 0.87 | CRBN (0.60) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL31390315 | 0.87 | CRBN (0.55) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL23250080 | 0.85 | DDB1 (0.52) | CRBNDDB1IKZF3TNFIL1B | |
| Trifluoroacetic Acid SCHEMBL31255493 | 0.85 | CRBN (0.51) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL24819465 | 0.85 | CRBN (0.58) | CRBNDDB1IKZF3TNFIL1B | |
| SCHEMBL30135913 | 0.85 | CRBN (0.58) | CRBNDDB1IKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536650-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |