Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 10/20 | 0.59 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.59 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 2/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26925699 | 1.00 | DDB1 (0.59) | DDB1CRBNTNKSPARP1CACNA2D1 | |
| SCHEMBL30705972 | 0.93 | DDB1 (0.54) | DDB1CRBNTNKSPARP1 | |
| SCHEMBL26925573 | 0.93 | DDB1 (0.54) | DDB1CRBNTNKSPARP1 | |
| SCHEMBL31236426 | 0.89 | DDB1 (0.62) | DDB1CRBNPARP1 | |
| SCHEMBL26927079 | 0.87 | CRBN (0.68) | DDB1CRBNPARP1 | |
| SCHEMBL26925117 | 0.87 | CRBN (0.68) | DDB1CRBNPARP1 | |
| SCHEMBL30731767 | 0.87 | CRBN (0.68) | DDB1CRBNPARP1 | |
| SCHEMBL30706225 | 0.87 | CRBN (0.68) | DDB1CRBNPARP1 | |
| SCHEMBL30706064 | 0.85 | DDB1 (0.60) | DDB1CRBN | |
| SCHEMBL26924779 | 0.85 | DDB1 (0.60) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536650-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| CN-119317623-A | Tricyclic quinolone BCL6 bifunctional degradation agents | 树线生物科学公司 | 2025-01-14 | — | — | CN | disclosed |
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |