SCHEMBL30732536

SCHEMBL30732536

C=CC[C@]1(C(=O)OC)C[C@H](OC(C)=O)[C@@H](NC(C)=O)[C@H]([C@H](OC(C)=O)[C@@H](CN=[N+]=[N-])OC(C)=O)O1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 1/20 0.31
▸ NEU4 Q8WWR8 1/20 0.31
▸ NEU3 Q9UQ49 1/20 0.31
▸ NEU2 Q9Y3R4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31695091 0.92 NANP (0.31) NANPNEU4NEU3NEU2
SCHEMBL31695113 0.82 — —
SCHEMBL31440877 0.80 NANP (0.36) NANPNEU4NEU3NEU2
SCHEMBL31695226 0.78 — —
SCHEMBL30732541 0.77 ABCB1 (0.33) —
SCHEMBL31695179 0.77 ABCB1 (0.33) —
SCHEMBL31225519 0.77 NEU4 (0.32) NEU4NEU3NEU2
SCHEMBL31225606 0.77 — —
SCHEMBL15090252 0.77 NANP (0.48) NANPNEU4NEU3NEU2
SCHEMBL16362518 0.77 NANP (0.48) NANPNEU4NEU3NEU2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2025-10-09 — — US disclosed
EP-4536653-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME Eisai R&D Management Co., Ltd. (JP) 2025-04-16 — — EP disclosed
WO-2023239906-A2 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME EISAI R&D MANAGEMENT CO., LTD. (JP) 2023-12-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250313574-A1 SIALIC ACID DERIVATIVES AND METHODS OF USING SAME NEU1, NEU2, NEU4 NANP 63/4885NEU4 3/4885NEU3 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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