Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 2/20 | 0.82 |
| ▸ | PRKAA1 | Q13131 | 7/20 | 0.72 |
| ▸ | PRKAA2 | P54646 | 6/20 | 0.72 |
| ▸ | KDR | P35968 | 10/20 | 0.68 |
| ▸ | TLK2 | Q86UE8 | 3/20 | 0.68 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.67 |
| ▸ | FGFR1 | P11362 | 7/20 | 0.67 |
| ▸ | FLT1 | P17948 | 2/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.66 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.66 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.66 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.66 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.66 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.66 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.66 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.66 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.66 |
| ▸ | PLK4 | O00444 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29486525 | 1.00 | ALK (0.82) | ALKPRKAA1PRKAA2KDRTLK2 | |
| SCHEMBL17503076 | 1.00 | ALK (0.82) | ALKPRKAA1PRKAA2KDRTLK2 | |
| SCHEMBL12329173 | 1.00 | ALK (0.82) | ALKPRKAA1PRKAA2KDRTLK2 | |
| SCHEMBL859965 | 0.90 | ALK (1.00) | ALKPRKAA1PRKAA2KDRTLK2 | |
| SCHEMBL859966 | 0.90 | ALK (1.00) | ALKPRKAA1PRKAA2KDRTLK2 | |
| SCHEMBL8210235 | 0.90 | ALK (0.83) | ALKPRKAA1PRKAA2KDRTLK2 | |
| SCHEMBL1081676 | 0.89 | ALK (0.82) | ALKPRKAA1PRKAA2KDRTLK2 | |
| SCHEMBL18814394 | 0.89 | ALK (0.82) | ALKPRKAA1PRKAA2KDRTLK2 | |
| SCHEMBL21966227 | 0.88 | PRKAA1 (0.80) | ALKPRKAA1PRKAA2KDRTLK2 | |
| SCHEMBL16085063 | 0.88 | ALK (0.80) | ALKPRKAA1PRKAA2KDRTLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117377495-A | Non-peptide targeted therapeutic agent and use thereof | 克林提克斯医药股份有限公司 | 2024-01-09 | — | — | CN | disclosed |