SCHEMBL30733463

SCHEMBL30733463

COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(=O)[nH]c3=O)C(OCC(=O)NC3CCCCCCC3)C2O)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TYMP P19971 2/20 0.44
P2RY14 Q15391 4/20 0.42
P2RY2 P41231 6/20 0.39
P2RY12 Q9H244 1/20 0.39
P2RY6 Q15077 4/20 0.38
P2RY4 P51582 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2525333 0.84 TYMP (0.47) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL18034343 0.84 TYMP (0.47) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL2525335 0.84 TYMP (0.47) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL15993943 0.84 TYMP (0.44) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL15993940 0.84 TYMP (0.44) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL7553293 0.84 TYMP (0.51) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL6831398 0.84 TYMP (0.51) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL6831397 0.84 TYMP (0.51) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL4451613 0.84 TYMP (0.51) TYMPP2RY14P2RY2P2RY6P2RY4
SCHEMBL19549038 0.84 TYMP (0.53) TYMPP2RY14P2RY2P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4547852-A2 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES Alnylam Pharmaceuticals, Inc. (US) 2025-05-07 EP disclosed
WO-2024006953-A2 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2024-01-04 WO disclosed