Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 11/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26635886 | 1.00 | NPY1R (0.43) | NPY1REEDKMT2ABRD4MCHR1 | |
| SCHEMBL26635881 | 1.00 | NPY1R (0.43) | NPY1REEDKMT2ABRD4MCHR1 | |
| SCHEMBL30735107 | 1.00 | NPY1R (0.43) | NPY1REEDKMT2ABRD4MCHR1 | |
| SCHEMBL26636104 | 1.00 | NPY1R (0.43) | NPY1REEDKMT2ABRD4MCHR1 | |
| SCHEMBL30735500 | 0.94 | NPY1R (0.45) | NPY1REEDKMT2A | |
| SCHEMBL30734529 | 0.94 | NPY1R (0.45) | NPY1REEDKMT2A | |
| SCHEMBL26637104 | 0.94 | NPY1R (0.45) | NPY1REEDKMT2A | |
| SCHEMBL26637097 | 0.94 | NPY1R (0.45) | NPY1REEDKMT2A | |
| SCHEMBL26637201 | 0.94 | NPY1R (0.45) | NPY1REEDKMT2A | |
| SCHEMBL30670075 | 0.93 | NPY1R (0.42) | NPY1REEDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519259-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215482-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |