Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26636260 | 1.00 | DDB1 (0.66) | DDB1CRBN | |
| SCHEMBL26636392 | 1.00 | DDB1 (0.66) | DDB1CRBN | |
| SCHEMBL26636397 | 1.00 | DDB1 (0.66) | DDB1CRBN | |
| SCHEMBL30663045 | 1.00 | DDB1 (0.66) | DDB1CRBN | |
| SCHEMBL30735142 | 0.94 | DDB1 (0.63) | DDB1CRBN | |
| SCHEMBL26636658 | 0.94 | DDB1 (0.63) | DDB1CRBN | |
| SCHEMBL26636662 | 0.94 | DDB1 (0.63) | DDB1CRBN | |
| SCHEMBL30735260 | 0.94 | DDB1 (0.63) | DDB1CRBN | |
| SCHEMBL26636849 | 0.94 | DDB1 (0.63) | DDB1CRBN | |
| SCHEMBL26635830 | 0.94 | DDB1 (0.68) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519259-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215482-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |