Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26636291 | 1.00 | KDM1A (0.47) | KDM1AGPR119KDM4EPKMPDE4A | |
| SCHEMBL26636285 | 1.00 | KDM1A (0.47) | KDM1AGPR119KDM4EPKMPDE4A | |
| SCHEMBL30657430 | 0.90 | KDM1A (0.56) | KDM1AGPR119PDE4APDE4BPDE4C | |
| SCHEMBL26639643 | 0.90 | KDM1A (0.56) | KDM1AGPR119PDE4APDE4BPDE4C | |
| SCHEMBL30735063 | 0.88 | FFAR4 (0.39) | — | |
| SCHEMBL26636882 | 0.88 | FFAR4 (0.39) | — | |
| SCHEMBL26636887 | 0.88 | FFAR4 (0.39) | — | |
| SCHEMBL30735027 | 0.87 | KDM1A (0.40) | KDM1AGPR119PDE4APDE4BPDE4C | |
| SCHEMBL30734463 | 0.87 | KDM1A (0.40) | KDM1AGPR119PDE4APDE4BPDE4C | |
| SCHEMBL26636549 | 0.87 | KDM1A (0.40) | KDM1AGPR119PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519259-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215482-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |