Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 9/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.41 |
| ▸ | HTR2C | P28335 | 6/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19297228 | 1.00 | SLC18A3 (0.42) | SLC18A3SIGMAR1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL19297028 | 0.81 | SLC18A3 (0.42) | SLC18A3SIGMAR1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL30735835 | 0.81 | SLC18A3 (0.42) | SLC18A3SIGMAR1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL19297033 | 0.80 | HTR2C (0.53) | SLC18A3SIGMAR1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL30735594 | 0.80 | HTR2C (0.53) | SLC18A3SIGMAR1HTR1ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL29862710 | 0.79 | HTR2C (0.42) | SLC18A3SIGMAR1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL19262502 | 0.73 | SLC6A2 (0.42) | HTR1ASLC6A2SLC6A4SLC6A3HRH3 | |
| SCHEMBL4962813 | 0.72 | MEN1 (0.43) | SLC18A3SIGMAR1HTR2CADRB2HTR2A | |
| SCHEMBL6275687 | 0.72 | HTR2C (0.50) | SLC18A3SIGMAR1HTR1ASLC6A2SLC6A4 | |
| SCHEMBL30735496 | 0.72 | HTR2C (0.50) | SLC18A3SIGMAR1HTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | SRX CARDIO, LLC (US) | 2024-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | PCSK9, PCSK6, PCSK7 | SLC18A3 4418/4885SIGMAR1 4853/4885HTR1A 3211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.