Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.49 |
| ▸ | CHUK | O15111 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | JAK1 | P23458 | 3/20 | 0.40 |
| ▸ | TYK2 | P29597 | 3/20 | 0.40 |
| ▸ | JAK3 | P52333 | 3/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19297230 | 1.00 | IKBKB (0.49) | IKBKBCHUKHTR2CADRB2SLC6A4 | |
| SCHEMBL30735595 | 0.85 | IKBKB (0.46) | IKBKBCHUKHTR2CSLC6A4JAK2 | |
| SCHEMBL19284588 | 0.85 | IKBKB (0.46) | IKBKBCHUKHTR2CSLC6A4JAK2 | |
| Hydrochloric Acid SCHEMBL19284589 | 0.84 | IKBKB (0.45) | IKBKBCHUKHTR2CSLC6A4JAK2 | |
| SCHEMBL30735531 | 0.77 | HTR1D (0.45) | IKBKBCHUKHTR2CSLC6A4JAK2 | |
| SCHEMBL19297195 | 0.77 | HTR1D (0.45) | IKBKBCHUKHTR2CSLC6A4JAK2 | |
| SCHEMBL3662883 | 0.75 | KDM1A (0.45) | IKBKBCHUKSLC6A4KDM1A | |
| SCHEMBL3662886 | 0.74 | SLC6A4 (0.41) | SLC6A4 | |
| SCHEMBL5321644 | 0.72 | JAK2 (0.47) | IKBKBCHUKHTR2CSLC6A4JAK2 | |
| SCHEMBL5324229 | 0.72 | HTR2C (0.50) | IKBKBCHUKHTR2CSLC6A4JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | SRX CARDIO, LLC (US) | 2024-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | PCSK9, PCSK6, PCSK7 | IKBKB 477/4885CHUK 604/4885HTR2C 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.