Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19297029 | 1.00 | HTR2C (0.50) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL30735577 | 0.94 | HTR2C (0.50) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL19297031 | 0.94 | HTR2C (0.50) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL19284557 | 0.81 | RPS6KA3 (0.51) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL30735609 | 0.81 | RPS6KA3 (0.51) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL19284657 | 0.81 | HTR2C (0.66) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL30735624 | 0.81 | HTR2C (0.66) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL19297189 | 0.78 | RPS6KA3 (0.42) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL19297102 | 0.78 | RPS6KA3 (0.51) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 | |
| SCHEMBL30735615 | 0.78 | RPS6KA3 (0.51) | HTR2CSLC6A2SLC6A4HTR1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | SRX CARDIO, LLC (US) | 2024-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11891369-B2 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | PCSK9, PCSK6, PCSK7 | HTR2C 3255/4885SLC6A2 4726/4885SLC6A4 4693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.