Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.47 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27344425 | 1.00 | KDM4E (0.48) | KDM4EEHMT1EZH2MAPTSMN1; SMN2 | |
| SCHEMBL27343122 | 0.93 | NPSR1 (0.50) | KDM4EEHMT1EZH2MAPTHTT | |
| SCHEMBL27343474 | 0.86 | KDM4E (0.39) | KDM4EMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL30736177 | 0.86 | KDM4E (0.39) | KDM4EMAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL27343123 | 0.84 | KDM4E (0.38) | KDM4EEHMT1EZH2MAPTSMN1; SMN2 | |
| SCHEMBL27342913 | 0.83 | KMT2A (0.44) | KDM4EMAPTSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL27343473 | 0.81 | KDM4E (0.36) | KDM4EEHMT1ALDH1A1MEN1KMT2A | |
| SCHEMBL27343467 | 0.78 | KMT2A (0.41) | EHMT1MEN1KMT2A | |
| SCHEMBL30735950 | 0.77 | EZH2 (0.46) | KDM4EEZH2MAPTSMN1; SMN2HTT | |
| SCHEMBL27344419 | 0.77 | EZH2 (0.46) | KDM4EEZH2MAPTSMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024003535-A2 | COMPOUNDS | UNIVERSITY OF DUNDEE (GB) | 2024-01-04 | — | — | WO | disclosed |