Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.80 |
| ▸ | MLNR | O43193 | 1/20 | 0.80 |
| ▸ | KDM1A | O60341 | 1/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.80 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.80 |
| ▸ | INSR | P06213 | 1/20 | 0.80 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.80 |
| ▸ | HTR1A | P08908 | 1/20 | 0.80 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.80 |
| ▸ | DRD2 | P14416 | 1/20 | 0.80 |
| ▸ | NQO2 | P16083 | 1/20 | 0.80 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.80 |
| ▸ | DRD1 | P21728 | 1/20 | 0.80 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.80 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.80 |
| ▸ | HTR2A | P28223 | 1/20 | 0.80 |
| ▸ | HTR2C | P28335 | 1/20 | 0.80 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.80 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17553468 | 1.00 | EGFR (1.00) | EGFRKCNH2MLNRKDM1AABCB11 | |
| SCHEMBL17553642 | 0.93 | EGFR (0.86) | EGFRKCNH2MLNRKDM1AABCB11 | |
| SCHEMBL17683137 | 0.92 | EGFR (0.85) | EGFRKCNH2MLNRKDM1AABCB11 | |
| SCHEMBL19114962 | 0.91 | EGFR (1.00) | EGFRKCNH2MLNRKDM1AABCB11 | |
| SCHEMBL17683053 | 0.90 | EGFR (0.82) | EGFRKCNH2MLNRKDM1AABCB11 | |
| SCHEMBL17683313 | 0.89 | EGFR (0.86) | EGFRKCNH2MLNRKDM1AABCB11 | |
| Osimertinib SCHEMBL14660911 | 0.89 | EGFR (1.00) | EGFRKCNH2MLNRKDM1AABCB11 | |
| Osimertinib SCHEMBL29378405 | 0.89 | EGFR (1.00) | EGFRKCNH2MLNRKDM1AABCB11 | |
| Osimertinib SCHEMBL29350904 | 0.89 | EGFR (1.00) | EGFRKCNH2MLNRKDM1AABCB11 | |
| SCHEMBL17553560 | 0.89 | EGFR (0.84) | EGFRKCNH2MLNRKDM1AABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4518858-A1 | INHIBITORS OF TAU PROTEINS | Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DE) | 2025-03-12 | — | — | EP | disclosed |
| CN-119562809-A | Inhibitors of tau protein | 德国神经退行性疾病研究中心 | 2025-03-04 | — | — | CN | disclosed |
| WO-2023213850-A1 | INHIBITORS OF TAU PROTEINS | DEUTSCHES ZENTRUM FÜR NEURODEGENERATIVE ERKRANKUNGEN E. V. (DZNE) (DE) | 2023-11-09 | — | — | WO | disclosed |