Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 3/20 | 0.38 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.37 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 6/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3095969 | 0.91 | PRKD3 (0.47) | NR1I3PRKD3MAP4K4CSNK1DFGFR1 | |
| SCHEMBL3086376 | 0.91 | PRKD3 (0.44) | NR1I3PRKD3MAP4K4CSNK1DFGFR1 | |
| SCHEMBL3079084 | 0.82 | PRKD3 (0.55) | PRKD3MAP4K4CSNK1DFGFR1MAPK9 | |
| SCHEMBL3092921 | 0.81 | PRKD3 (0.44) | PRKD3MAP4K4CSNK1DFGFR1MAPK9 | |
| SCHEMBL3092438 | 0.79 | PRKD3 (0.43) | PRKD3MAP4K4CSNK1DFGFR1MAPK9 | |
| SCHEMBL3083884 | 0.78 | PRKD3 (0.48) | PRKD3MAP4K4CSNK1DFGFR1MAPK9 | |
| SCHEMBL3085618 | 0.74 | NR1I2 (0.37) | NR1I3PRKD3MAP4K4CSNK1DMAPK9 | |
| SCHEMBL4298583 | 0.69 | MAP4K4 (0.54) | PRKD3MAP4K4CSNK1DFGFR1MAPK9 | |
| SCHEMBL13144044 | 0.68 | MAP4K4 (0.59) | PRKD3MAP4K4CSNK1DFGFR1MAPK9 | |
| SCHEMBL4301905 | 0.66 | PRKD3 (0.49) | PRKD3MAP4K4CSNK1DFGFR1MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790741-B2 | Imidazothiazoles and imidazoxazoles | ABBOTT LABORATORIES (US) | 2010-09-07 | — | — | US | disclosed |
| US-20080161341-A1 | Novel imidazothiazoles and imidazoxazoles | ABBVIE INC. | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161341-A1 | Novel imidazothiazoles and imidazoxazoles | MAP3K1, MAP3K19, MAP3K5 | NR1I3 515/4885PRKD3 376/4885MAP4K4 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.