Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.63 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31436325 | 1.00 | MAPT (0.75) | MAPTKDM4EHSP90AA1CYP3A4MEN1 | |
| SCHEMBL31436345 | 0.86 | HSP90AA1 (0.61) | MAPTKDM4EHSP90AA1CYP3A4MEN1 | |
| SCHEMBL30736515 | 0.86 | HSP90AA1 (0.61) | MAPTKDM4EHSP90AA1CYP3A4MEN1 | |
| SCHEMBL1933655 | 0.86 | MAPT (1.00) | MAPTKDM4EHSP90AA1CYP3A4MEN1 | |
| SCHEMBL1933659 | 0.86 | MAPT (1.00) | MAPTKDM4EHSP90AA1CYP3A4MEN1 | |
| SCHEMBL6292775 | 0.84 | HSP90AA1 (1.00) | MAPTKDM4EHSP90AA1CYP3A4MEN1 | |
| SCHEMBL1042207 | 0.81 | HSP90AA1 (0.67) | MAPTKDM4EHSP90AA1ALDH1A1NPSR1 | |
| SCHEMBL1042209 | 0.81 | HSP90AA1 (0.67) | MAPTKDM4EHSP90AA1ALDH1A1NPSR1 | |
| SCHEMBL30736435 | 0.81 | HSP90AA1 (0.70) | MAPTKDM4EHSP90AA1MEN1KMT2A | |
| SCHEMBL28931388 | 0.81 | HSP90AA1 (0.70) | MAPTKDM4EHSP90AA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250228795-A1 | ESTROGENIC COMPOUNDS AND METHODS OF USE | IATERION, INC. | 2025-07-17 | — | — | US | disclosed |
| EP-4561560-A1 | ESTROGENIC COMPOUNDS AND METHODS OF USE | Iaterion, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-119677514-A | Estrogenic compounds and methods of use | 益特瑞恩公司 | 2025-03-21 | — | — | CN | disclosed |
| WO-2024026034-A1 | ESTROGENIC COMPOUNDS AND METHODS OF USE | IATERION, INC. (US) | 2024-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250228795-A1 | ESTROGENIC COMPOUNDS AND METHODS OF USE | ESR1, ESR2, CYP19A1 | MAPT 2361/4885KDM4E 1267/4885HSP90AA1 1045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.