SCHEMBL30736941

SCHEMBL30736941

Cc1cc(C)c(C2=C(OCc3ccccc3)C3(CCC(OC4CCN(C(=O)OC(C)(C)C)CC4)CC3)OC2=O)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
YAP1 P46937 3/20 0.41
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
PRMT5 O14744 4/20 0.39
STS P08842 1/20 0.39
GPR119 Q8TDV5 3/20 0.38
CSF1R P07333 2/20 0.38
TP53 P04637 2/20 0.38
LMNA P02545 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
OPRD1 P41143 1/20 0.37
OPRK1 P41145 1/20 0.37
GAA P10253 1/20 0.37
THRB P10828 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KDR P35968 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27379453 0.88 TP53 (0.38) YAP1MEN1KMT2APRMT5CSF1R
SCHEMBL27379765 0.88 TP53 (0.38) YAP1MEN1KMT2APRMT5CSF1R
SCHEMBL27379718 0.88 TP53 (0.38) YAP1MEN1KMT2APRMT5CSF1R
SCHEMBL27378963 0.86 HTR2A (0.35) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL27378835 0.86 HTR2A (0.35) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL27379038 0.86 HTR2A (0.35) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL27378530 0.86 HTR2A (0.35) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL27378302 0.86 HTR2A (0.35) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL27378706 0.86 HTR2A (0.35) MEN1KMT2ALMNAPOLBMAPT
SCHEMBL27377920 0.86 HTR2A (0.35) MEN1KMT2ALMNAPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580405-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL Oerth Bio LLC (US) 2025-07-09 EP disclosed
WO-2024050016-A9 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-04-03 WO disclosed
WO-2024050016-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2024-03-07 WO disclosed