SCHEMBL30737508

SCHEMBL30737508

C#CCOCCOCCOCCOCCOc1cccc(Oc2ccc(C(=O)OC)cn2)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
RAB9A P51151 1/20 0.43
LMNA P02545 3/20 0.42
KDM4E B2RXH2 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.39
LIPE Q05469 1/20 0.39
GABRA5 P31644 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.38
BRCA1 P38398 1/20 0.38
HBB P68871 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TSHR P16473 1/20 0.38
MAPK1 P28482 2/20 0.37
HRH3 Q9Y5N1 2/20 0.37
PPARG P37231 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737459 0.92 KDM4E (0.44) KDM4EALDH1A1SMN1; SMN2KMT2AHRH3
SCHEMBL30737301 0.88 HRH3 (0.38) MAPTLMNAKDM4EALDH1A1HPGD
SCHEMBL30737465 0.86 MAPT (0.45) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL30737383 0.86 MAPT (0.45) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL30737488 0.86 MAPT (0.45) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL31646216 0.85 MAPT (0.50) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL30737156 0.83 MAPT (0.44) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL30737281 0.83 HRH3 (0.36) RAB9ALMNALIPEKMT2AHRH3
SCHEMBL31724770 0.80 BCHE (0.44) MAPTRAB9ALMNAKDM4EALDH1A1
SCHEMBL30737371 0.80 BCHE (0.44) MAPTRAB9ALMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed