Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 1.00 |
| ▸ | FGFR1 | P11362 | 16/20 | 1.00 |
| ▸ | FLT1 | P17948 | 16/20 | 1.00 |
| ▸ | FLT4 | P35916 | 16/20 | 1.00 |
| ▸ | FGFR2 | P21802 | 15/20 | 1.00 |
| ▸ | FGFR4 | P22455 | 15/20 | 1.00 |
| ▸ | FGFR3 | P22607 | 15/20 | 1.00 |
| ▸ | LCK | P06239 | 3/20 | 0.82 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.82 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26928515 | 1.00 | KDR (1.00) | KDRFGFR1FLT1FLT4FGFR2 | |
| SCHEMBL26928289 | 0.93 | KDR (1.00) | KDRFGFR1FLT1FLT4FGFR2 | |
| SCHEMBL27218182 | 0.92 | KDR (1.00) | KDRFGFR1FLT1FLT4FGFR2 | |
| SCHEMBL5606176 | 0.91 | KDR (1.00) | KDRFGFR1FLT1FLT4FGFR2 | |
| SCHEMBL30737824 | 0.91 | KDR (1.00) | KDRFGFR1FLT1FLT4FGFR2 | |
| SCHEMBL27218116 | 0.91 | KDR (1.00) | KDRFGFR1FLT1FLT4FGFR2 | |
| SCHEMBL26928301 | 0.90 | KDR (1.00) | KDRFGFR1FLT1FLT4FGFR2 | |
| SCHEMBL5605870 | 0.89 | KDR (1.00) | KDRFGFR1FLT1FLT4FGFR2 | |
| SCHEMBL30737906 | 0.88 | KDR (1.00) | KDRFGFR1FLT1FLT4FGFR2 | |
| SCHEMBL5606197 | 0.88 | KDR (1.00) | KDRFGFR1FLT1FLT4FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240271-A1 | USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY | FOUNTAIN THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | claimed |
| WO-2023240271-A1 | USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY | FOUNTAIN THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | disclosed |