Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 11/20 | 0.86 |
| ▸ | FLT1 | P17948 | 11/20 | 0.86 |
| ▸ | KDR | P35968 | 1/20 | 0.86 |
| ▸ | ABL1 | P00519 | 14/20 | 0.67 |
| ▸ | BCR | P11274 | 5/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218191 | 1.00 | FGFR1 (0.86) | FGFR1FLT1KDRABL1BCR | |
| SCHEMBL5866782 | 0.99 | FGFR1 (0.84) | FGFR1FLT1KDRABL1BCR | |
| SCHEMBL3538743 | 0.98 | FGFR1 (0.83) | FGFR1FLT1KDRABL1BCR | |
| SCHEMBL3544701 | 0.97 | FGFR1 (0.81) | FGFR1FLT1KDRABL1BCR | |
| SCHEMBL5866709 | 0.93 | FGFR1 (0.74) | FGFR1FLT1KDRABL1BCR | |
| SCHEMBL3541477 | 0.92 | FGFR1 (0.73) | FGFR1FLT1KDRABL1BCR | |
| SCHEMBL3534684 | 0.92 | FGFR1 (0.98) | FGFR1FLT1KDRABL1BCR | |
| SCHEMBL3532746 | 0.91 | FGFR1 (0.72) | FGFR1FLT1KDRABL1BCR | |
| SCHEMBL3538447 | 0.89 | FGFR1 (0.69) | FGFR1FLT1KDRABL1BCR | |
| SCHEMBL26928241 | 0.89 | FGFR1 (0.69) | FGFR1FLT1KDRABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240271-A1 | USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY | FOUNTAIN THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | claimed |
| WO-2023240271-A1 | USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY | FOUNTAIN THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | disclosed |