Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 13/20 | 1.00 |
| ▸ | FGFR4 | P22455 | 9/20 | 1.00 |
| ▸ | FGFR1 | P11362 | 5/20 | 1.00 |
| ▸ | FGFR2 | P21802 | 5/20 | 1.00 |
| ▸ | FGFR3 | P22607 | 5/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 3/20 | 1.00 |
| ▸ | PDGFRA | P16234 | 3/20 | 1.00 |
| ▸ | KDR | P35968 | 3/20 | 1.00 |
| ▸ | FYN | P06241 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 1.00 |
| ▸ | EPHB3 | P54753 | 2/20 | 1.00 |
| ▸ | PRKACA | P17612 | 1/20 | 0.85 |
| ▸ | PRKACG | P22612 | 1/20 | 0.85 |
| ▸ | PRKACB | P22694 | 1/20 | 0.85 |
| ▸ | CSF1R | P07333 | 3/20 | 0.52 |
| ▸ | PRKDC | P78527 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5772113 | 1.00 | EGFR (1.00) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL5832196 | 1.00 | EGFR (1.00) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL5772118 | 1.00 | EGFR (1.00) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL27218145 | 1.00 | EGFR (1.00) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL5811223 | 1.00 | EGFR (1.00) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL30737937 | 1.00 | EGFR (1.00) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL5831546 | 0.95 | EGFR (0.90) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL5767065 | 0.95 | EGFR (0.90) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL5830777 | 0.93 | EGFR (0.87) | EGFRFGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL5830774 | 0.93 | EGFR (0.87) | EGFRFGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240271-A1 | USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY | FOUNTAIN THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | claimed |
| WO-2023240271-A1 | USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY | FOUNTAIN THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | disclosed |