Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 17/20 | 0.71 |
| ▸ | KLK1 | P06870 | 3/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739106 | 0.91 | KLKB1 (0.73) | KLKB1KLK1ITK | |
| SCHEMBL30739086 | 0.89 | KLKB1 (0.56) | KLKB1KLK1SNCA | |
| SCHEMBL30739069 | 0.88 | KLKB1 (0.55) | KLKB1KLK1 | |
| SCHEMBL1981938 | 0.84 | KLKB1 (1.00) | KLKB1KLK1 | |
| SCHEMBL31591059 | 0.83 | KLKB1 (0.52) | KLKB1AURKAITK | |
| Hydrochloric Acid SCHEMBL1985633 | 0.83 | KLKB1 (0.98) | KLKB1KLK1 | |
| SCHEMBL30739171 | 0.83 | KLKB1 (0.69) | KLKB1KLK1 | |
| SCHEMBL30739146 | 0.82 | KLKB1 (0.77) | KLKB1KLK1 | |
| SCHEMBL30739270 | 0.81 | KLKB1 (0.67) | KLKB1KLK1 | |
| Acetic Acid SCHEMBL29253774 | 0.81 | KLKB1 (0.94) | KLKB1KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561993-A1 | INHIBITORS OF PLASMA KALLIKREIN | Rezolute, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024025907-A1 | INHIBITORS OF PLASMA KALLIKREIN | REZOLUTE, INC. (US) | 2024-02-01 | — | — | WO | disclosed |