Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 7/20 | 0.38 |
| ▸ | BTK | Q06187 | 6/20 | 0.38 |
| ▸ | CSF1R | P07333 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | ITK | Q08881 | 1/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 2/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739448 | 0.91 | FGFR1 (0.47) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL29178755 | 0.90 | FGFR1 (0.51) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL29178793 | 0.88 | FGFR1 (0.50) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL30739150 | 0.88 | FGFR1 (0.50) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL30739288 | 0.87 | CYP3A4 (0.43) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL29178647 | 0.87 | FGFR1 (0.47) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL30739330 | 0.85 | FGFR1 (0.54) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL30739362 | 0.83 | SMN1; SMN2 (0.44) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL29178890 | 0.81 | CYP3A4 (0.46) | FGFR1FGFR4FGFR2FGFR3CYP3A4 | |
| SCHEMBL30739403 | 0.81 | CYP3A4 (0.46) | FGFR1FGFR4FGFR2FGFR3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |