Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.46 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.46 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 8/20 | 0.37 |
| ▸ | BLK | P51451 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | ITK | Q08881 | 2/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178714 | 1.00 | CYP3A4 (0.46) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL29178754 | 0.93 | CYP3A4 (0.43) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739331 | 0.93 | CYP3A4 (0.43) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739346 | 0.93 | CYP3A4 (0.46) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739263 | 0.92 | CYP3A4 (0.47) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL29178898 | 0.92 | CYP3A4 (0.45) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739336 | 0.92 | CYP3A4 (0.45) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739161 | 0.91 | CYP3A4 (0.47) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL29178813 | 0.91 | CYP3A4 (0.45) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739365 | 0.91 | CYP3A4 (0.45) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |