Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.37 |
| ▸ | FEN1 | P39748 | 4/20 | 0.37 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 5/20 | 0.31 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.31 |
| ▸ | RAF1 | P04049 | 2/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739118 | 0.94 | CYP3A4 (0.41) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739224 | 0.92 | CYP3A4 (0.40) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739266 | 0.92 | CYP3A4 (0.40) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739324 | 0.90 | CYP3A4 (0.41) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739353 | 0.90 | CYP3A4 (0.46) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL29178906 | 0.90 | CYP3A4 (0.46) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739370 | 0.90 | CYP3A4 (0.39) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL29178858 | 0.90 | CYP3A4 (0.39) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739315 | 0.90 | CYP3A4 (0.39) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 | |
| SCHEMBL30739296 | 0.89 | CYP3A4 (0.41) | CYP3A4CYP2D6FGFR1CYP2C9FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |