Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | FEN1 | P39748 | 2/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 4/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739425 | 0.85 | CYP3A4 (0.38) | MAP4K4TNK2PIK3CDCYP3A4CYP2D6 | |
| SCHEMBL30739135 | 0.80 | JAK2 (0.38) | MAP4K4PIK3CDCSF1R | |
| SCHEMBL29178906 | 0.76 | CYP3A4 (0.46) | MAP4K4ALOX5APFEN1TNK2CYP3A4 | |
| SCHEMBL30739353 | 0.76 | CYP3A4 (0.46) | MAP4K4ALOX5APFEN1TNK2CYP3A4 | |
| SCHEMBL30739175 | 0.75 | CYP3A4 (0.44) | MAP4K4ALOX5APFEN1TNK2CYP3A4 | |
| SCHEMBL29178879 | 0.75 | CYP3A4 (0.44) | MAP4K4ALOX5APFEN1TNK2CYP3A4 | |
| SCHEMBL30739213 | 0.75 | CYP3A4 (0.45) | MAP4K4ALOX5APFEN1TNK2CYP3A4 | |
| SCHEMBL29178681 | 0.75 | CYP3A4 (0.45) | MAP4K4ALOX5APFEN1TNK2CYP3A4 | |
| SCHEMBL30739197 | 0.73 | CYP3A4 (0.44) | MAP4K4ALOX5APFEN1TNK2PIK3CD | |
| SCHEMBL30739301 | 0.70 | MAP4K4 (0.42) | MAP4K4KDM4EHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |