SCHEMBL30739715

SCHEMBL30739715

COc1ccc(/C=C/c2cc(Cl)cc(C(F)(F)F)c2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 3/20 0.71
RELA Q04206 1/20 0.56
ESR1 P03372 2/20 0.53
CYP1A1 P04798 2/20 0.53
PTGS2 P35354 2/20 0.53
CYP1B1 Q16678 2/20 0.53
TUBB1 Q9H4B7 2/20 0.53
CYP1A2 P05177 2/20 0.53
ABL1 P00519 1/20 0.53
TTR P02766 1/20 0.53
ABCB1 P08183 1/20 0.53
ALOX5 P09917 1/20 0.53
BCR P11274 1/20 0.53
CYP19A1 P11511 1/20 0.53
NQO2 P16083 1/20 0.53
TUBB4A P04350 1/20 0.53
TUBB P07437 1/20 0.53
TUBA3C P0DPH7 1/20 0.53
TUBA1B P68363 1/20 0.53
TUBA4A P68366 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18144159 1.00 AHR (0.71) AHRRELAESR1CYP1A1PTGS2
SCHEMBL18144154 1.00 AHR (0.71) AHRRELAESR1CYP1A1PTGS2
SCHEMBL18144142 0.89 CYP1A1 (0.61) AHRRELAESR1CYP1A1PTGS2
SCHEMBL18144139 0.89 CYP1A1 (0.61) AHRRELAESR1CYP1A1PTGS2
SCHEMBL6461016 0.84 AHR (1.00) AHRRELAESR1CYP1A1PTGS2
SCHEMBL6471618 0.84 AHR (1.00) AHRRELAESR1CYP1A1PTGS2
SCHEMBL6471614 0.84 AHR (1.00) AHRRELAESR1CYP1A1PTGS2
SCHEMBL18144100 0.80 CYP1A1 (0.67) AHRRELAESR1CYP1A1PTGS2
SCHEMBL18144097 0.80 CYP1A1 (0.67) AHRRELAESR1CYP1A1PTGS2
SCHEMBL18144113 0.80 AHR (0.77) AHRRELAESR1CYP1A1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed