SCHEMBL30739735

SCHEMBL30739735

Cc1c(F)ccc(NC(=O)OC(C)(C)C)c1F

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP17A1 P05093 1/20 0.44
KCNQ4 P56696 3/20 0.40
KCNQ5 Q9NR82 3/20 0.40
RXFP1 Q9HBX9 2/20 0.39
EPHX2 P34913 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
BRD9 Q9H8M2 1/20 0.38
PKM P14618 1/20 0.37
ELANE P08246 1/20 0.37
CTRB1 P17538 1/20 0.37
HPGD P15428 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
METAP1 P53582 1/20 0.36
BRAF P15056 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31455160 0.85 CYP17A1 (0.43) CYP17A1KCNQ4KCNQ5RXFP1LMNA
SCHEMBL25681427 0.85 CYP17A1 (0.43) CYP17A1KCNQ4KCNQ5RXFP1LMNA
SCHEMBL31607582 0.85 CYP17A1 (0.43) CYP17A1KCNQ4KCNQ5RXFP1LMNA
SCHEMBL7008829 0.84 CYP17A1 (0.44) CYP17A1KCNQ4KCNQ5RXFP1EPHX2
SCHEMBL31500450 0.84 ATR (0.43) CYP17A1KCNQ4KCNQ5LMNAPOLB
SCHEMBL30673347 0.84 ATR (0.43) CYP17A1KCNQ4KCNQ5LMNAPOLB
SCHEMBL24731578 0.84 CYP17A1 (0.40) CYP17A1KCNQ4KCNQ5RXFP1LMNA
SCHEMBL30641931 0.84 CYP17A1 (0.40) CYP17A1KCNQ4KCNQ5RXFP1LMNA
SCHEMBL20578044 0.84 CYP17A1 (0.42) CYP17A1KCNQ4KCNQ5RXFP1EPHX2
SCHEMBL31009176 0.83 CYP17A1 (0.44) CYP17A1KCNQ4KCNQ5RXFP1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed