Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | CCNK | O75909 | 1/20 | 0.37 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20295597 | 1.00 | POLB (0.44) | POLBGPR119PRMT5HPGDSTP53 | |
| SCHEMBL25297123 | 0.78 | POLB (0.43) | POLBGPR119HPGDSTP53MAPT | |
| SCHEMBL27104608 | 0.78 | POLB (0.52) | POLBGPR119MAPTWNT3ACCNK | |
| SCHEMBL20757641 | 0.78 | PDE4B (0.46) | POLBGPR119USP30CCNKCDK12 | |
| SCHEMBL30094557 | 0.78 | PDE4B (0.46) | POLBGPR119USP30CCNKCDK12 | |
| SCHEMBL30394540 | 0.77 | DDB1 (0.46) | POLBGPR119HPGDSTP53MAPT | |
| SCHEMBL255458 | 0.77 | DDB1 (0.46) | POLBGPR119HPGDSTP53MAPT | |
| SCHEMBL20295862 | 0.76 | CD274 (0.41) | GPR119WNT3ACCNKCDK12 | |
| SCHEMBL31479234 | 0.76 | PDE4B (0.40) | GPR119TP53MAPTUSP30WNT3A | |
| SCHEMBL3328004 | 0.76 | PIK3CA (0.54) | PRMT5KDM4EPDE4BDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110582493-B | Benzoxazole derivatives as immunomodulators | 因赛特公司 | 2024-03-08 | — | — | CN | disclosed |