Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | WEE1 | P30291 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29180488 | 1.00 | GRM5 (0.35) | GRM5KDM4CNPC1RAB9AGCK | |
| SCHEMBL19715648 | 0.86 | GRM5 (0.36) | GRM5KDM4CNPC1RAB9AGCK | |
| SCHEMBL30452675 | 0.82 | GRM5 (0.35) | GRM5KDM4CNPC1RAB9AGCK | |
| SCHEMBL29068007 | 0.82 | GRM5 (0.35) | GRM5KDM4CNPC1RAB9AGCK | |
| SCHEMBL29180444 | 0.82 | GRM5 (0.37) | GRM5KDM4CNPC1RAB9AGCK | |
| SCHEMBL30801034 | 0.82 | GRM5 (0.37) | GRM5KDM4CNPC1RAB9AGCK | |
| SCHEMBL22576701 | 0.81 | KDM4C (0.41) | GRM5KDM4CNPC1RAB9AGCK | |
| SCHEMBL19715695 | 0.80 | KDM4C (0.35) | KDM4CNPC1RAB9AL3MBTL1TRPV3 | |
| SCHEMBL25279093 | 0.80 | GRM5 (0.36) | GRM5KDM4CNPC1RAB9AGCK | |
| SCHEMBL29180483 | 0.79 | KDM4C (0.39) | GRM5KDM4CNPC1RAB9AGCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024022314-A1 | TRIAZOLE COMPOUNDS AND USE THEREOF AS LPAR1 ANTAGONIST | 武汉人福创新药物研发中心有限公司 | 2024-02-01 | — | — | WO | disclosed |
| CN-117447450-A | Triazole compounds and their use as LPAR1 antagonists | 武汉人福创新药物研发中心有限公司 | 2024-01-26 | — | — | CN | disclosed |