SCHEMBL30740412

SCHEMBL30740412

C[C@@H]1CC(O)OC2=C1C(=O)CCC2

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
ALDH1A1 P00352 2/20 0.34
ALOX15 P16050 1/20 0.34
RECQL P46063 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
OPRD1 P41143 1/20 0.32
MAPT P10636 2/20 0.31
HPGD P15428 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30740403 1.00 TP53 (0.37) TP53ALDH1A1ALOX15RECQLMEN1
SCHEMBL30740360 1.00 TP53 (0.37) TP53ALDH1A1ALOX15RECQLMEN1
SCHEMBL30740408 0.82 TP53 (0.39) TP53ALDH1A1ALOX15RECQLMEN1
SCHEMBL30740456 0.80 TP53 (0.42) TP53ALDH1A1ALOX15RECQLMEN1
SCHEMBL30740406 0.80 TP53 (0.42) TP53ALDH1A1ALOX15RECQLMEN1
SCHEMBL30740430 0.80 TP53 (0.42) TP53ALDH1A1ALOX15RECQLMEN1
SCHEMBL30740337 0.80 TP53 (0.33) TP53ALDH1A1ALOX15RECQL
SCHEMBL30740387 0.79 MEN1 (0.36) TP53ALDH1A1ALOX15RECQLMEN1
SCHEMBL31425651 0.78 TP53 (0.36) TP53ALDH1A1ALOX15RECQLMEN1
SCHEMBL31425623 0.78 TP53 (0.36) TP53ALDH1A1ALOX15RECQLMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4561997-A1 CHROMEN-5-ONE DERIVATIVES FOR USE AS FRAGRANCES Givaudan SA (CH) 2025-06-04 EP disclosed
CN-119604490-A Chromen-5-one derivatives for use as fragrances 奇华顿股份有限公司 2025-03-11 CN disclosed
WO-2024023169-A1 CHROMEN-5-ONE DERIVATIVES FOR USE AS FRAGRANCES GIVAUDAN SA (CH) 2024-02-01 WO disclosed