Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 8/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740736 | 0.86 | MRGPRX4 (0.64) | MRGPRX4POLBNPC1RAB9AKMT2A | |
| SCHEMBL3152910 | 0.75 | MRGPRX4 (0.53) | MRGPRX4KMT2AS1PR4MAPTTP53 | |
| SCHEMBL3148906 | 0.75 | MRGPRX4 (0.53) | MRGPRX4POLBNPC1RAB9AKMT2A | |
| SCHEMBL24793360 | 0.75 | HPGD (0.55) | MRGPRX4POLBNPC1RAB9AKMT2A | |
| SCHEMBL30745399 | 0.75 | HPGD (0.55) | MRGPRX4POLBNPC1RAB9AKMT2A | |
| SCHEMBL29826789 | 0.74 | KMT2A (0.49) | MRGPRX4POLBNPC1RAB9AKMT2A | |
| SCHEMBL22480845 | 0.74 | MRGPRX4 (1.00) | MRGPRX4POLBNPC1RAB9AKMT2A | |
| SCHEMBL22469924 | 0.73 | MRGPRX4 (0.58) | MRGPRX4NPC1RAB9AKMT2AS1PR4 | |
| SCHEMBL22480484 | 0.73 | MRGPRX4 (1.00) | MRGPRX4S1PR4CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL22480888 | 0.72 | MRGPRX4 (0.74) | MRGPRX4NPC1RAB9AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |