Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.74 |
| ▸ | KMO | O15229 | 1/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | TTR | P02766 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29103540 | 1.00 | MRGPRX4 (0.74) | MRGPRX4KMOAKR1C3ALDH1A1MAPT | |
| SCHEMBL15011479 | 0.89 | MRGPRX4 (0.66) | MRGPRX4KMOAKR1C3ALDH1A1MAPT | |
| SCHEMBL31568461 | 0.85 | MRGPRX4 (1.00) | MRGPRX4KMOAKR1C3ALDH1A1MAPT | |
| SCHEMBL9005664 | 0.85 | MRGPRX4 (0.60) | MRGPRX4KMOAKR1C3IDO1TTR | |
| SCHEMBL10668436 | 0.85 | MRGPRX4 (1.00) | MRGPRX4KMOAKR1C3ALDH1A1MAPT | |
| SCHEMBL27108465 | 0.83 | MRGPRX4 (0.62) | MRGPRX4KMOAKR1C3TTRRAB9A | |
| SCHEMBL10674162 | 0.83 | MRGPRX4 (0.74) | MRGPRX4KMOAKR1C3ALDH1A1MAPT | |
| SCHEMBL11151654 | 0.82 | MRGPRX4 (0.73) | MRGPRX4KMOAKR1C3TTRNPC1 | |
| SCHEMBL27373055 | 0.81 | MRGPRX4 (0.55) | MRGPRX4ALDH1A1TTR | |
| SCHEMBL2857675 | 0.80 | AKR1C3 (0.73) | MRGPRX4KMOAKR1C3ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |