Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | KDM5C | P41229 | 2/20 | 0.57 |
| ▸ | KDM6B | O15054 | 1/20 | 0.57 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.57 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.47 |
| ▸ | KDM5A | P29375 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL348975 | 1.00 | KDM4C (0.57) | KDM4CKDM4EKDM5CKDM6BKDM2A | |
| SCHEMBL10263738 | 0.86 | KDM4E (0.57) | KDM4CKDM4EKDM5CKDM6BKDM2A | |
| SCHEMBL31320065 | 0.86 | KDM4E (0.57) | KDM4CKDM4EKDM5CKDM6BKDM2A | |
| SCHEMBL29700409 | 0.85 | KDM4E (0.55) | KDM4CKDM4EKDM5CKDM6BKDM2A | |
| SCHEMBL22005801 | 0.85 | KDM5C (0.55) | KDM4CKDM4EKDM5CKDM6BKDM2A | |
| SCHEMBL4450004 | 0.85 | KDM4E (0.55) | KDM4CKDM4EKDM5CKDM6BKDM2A | |
| SCHEMBL1007105 | 0.85 | KDM4E (0.55) | KDM4CKDM4EKDM5CKDM6BKDM2A | |
| SCHEMBL16215925 | 0.85 | KDM4C (0.55) | KDM4CKDM4EKDM5CKDM6BKDM2A | |
| SCHEMBL30378291 | 0.85 | KDM4C (0.55) | KDM4CKDM4EKDM5CKDM6BKDM2A | |
| SCHEMBL1287072 | 0.85 | KDM4C (0.55) | KDM4CKDM4EKDM5CKDM6BKDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4702025-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2026-03-04 | — | — | EP | disclosed |
| WO-2024223715-A1 | BICYCLIC HETEROCYCLE COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-10-31 | — | — | WO | disclosed |
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |