Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 15/20 | 0.47 |
| ▸ | NPY1R | P25929 | 9/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.47 |
| ▸ | NPY2R | P49146 | 5/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30193198 | 0.96 | NPY4R (0.45) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| SCHEMBL31410639 | 0.94 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RMME | |
| SCHEMBL31127534 | 0.94 | NPY4R (0.42) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| SCHEMBL31461910 | 0.92 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL30042675 | 0.92 | NPY4R (0.53) | NPY4RNPY1RNPY5RNPY2RMME | |
| SCHEMBL30317611 | 0.91 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| SCHEMBL31267155 | 0.90 | NPY4R (0.54) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| SCHEMBL29678407 | 0.90 | NPY4R (0.47) | NPY4RNPY1RNPY5RNPY2RNMT2 | |
| SCHEMBL30786580 | 0.90 | NPY4R (0.49) | NPY4RNPY1RNPY5RNPY2ROPRM1 | |
| SCHEMBL29436277 | 0.89 | NPY4R (0.44) | NPY4RNPY1RNPY5RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4368249-A2 | DNA MODIFYING FUSION PROTEINS AND METHODS OF USE THEREOF | The General Hospital Corporation (US) | 2024-05-15 | — | — | EP | disclosed |
| EP-3744835-B1 | DNA MODIFYING FUSION PROTEINS AND METHODS OF USE THEREOF | MASSACHUSETTS GEN HOSPITAL (US) | 2024-01-31 | — | — | EP | disclosed |