Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | GRM1 | Q13255 | 7/20 | 0.43 |
| ▸ | GRM5 | P41594 | 6/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16824861 | 1.00 | PDK4 (0.49) | PDK4HTR6ALDH1A1LMNAMAPT | |
| SCHEMBL522085 | 0.87 | PDK4 (0.52) | PDK4HTR6ALDH1A1LMNAMAPT | |
| SCHEMBL29864873 | 0.87 | PDK4 (0.52) | PDK4HTR6ALDH1A1LMNAMAPT | |
| SCHEMBL29535433 | 0.86 | PDK4 (0.51) | PDK4HTR6ALDH1A1LMNAMAPT | |
| SCHEMBL10036179 | 0.86 | PDK4 (0.51) | PDK4HTR6ALDH1A1LMNAMAPT | |
| SCHEMBL16385571 | 0.86 | PDK4 (0.51) | PDK4HTR6ALDH1A1LMNAMAPT | |
| SCHEMBL282496 | 0.85 | PDK4 (0.50) | PDK4HTR6ALDH1A1LMNAMAPT | |
| SCHEMBL6365955 | 0.85 | PDK4 (0.52) | PDK4HTR6ALDH1A1LMNAMAPT | |
| SCHEMBL519962 | 0.84 | PDK4 (0.49) | PDK4HTR6ALDH1A1LMNAMAPT | |
| SCHEMBL5004734 | 0.84 | PDK4 (0.51) | PDK4HTR6ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024015346-A1 | CEREBLON LIGANDS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. d.b.a PROTEOVANT THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |