Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 15/20 | 0.84 |
| ▸ | NTRK2 | Q16620 | 15/20 | 0.84 |
| ▸ | IGF1R | P08069 | 5/20 | 0.84 |
| ▸ | FGFR1 | P11362 | 5/20 | 0.84 |
| ▸ | NTRK3 | Q16288 | 11/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295541 | 1.00 | NTRK1 (0.84) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL21295407 | 0.92 | NTRK1 (1.00) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL21305495 | 0.92 | NTRK1 (0.95) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL30743942 | 0.92 | NTRK1 (0.95) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL23051395 | 0.89 | NTRK1 (0.86) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL21295396 | 0.89 | NTRK1 (0.86) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL30743944 | 0.89 | NTRK1 (0.86) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL21295434 | 0.87 | NTRK1 (0.90) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL21295556 | 0.85 | NTRK1 (0.79) | NTRK1NTRK2IGF1RFGFR1NTRK3 | |
| SCHEMBL30743928 | 0.85 | NTRK1 (0.79) | NTRK1NTRK2IGF1RFGFR1NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |