Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 6/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 3/20 | 0.31 |
| ▸ | PPARG | P37231 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801137 | 1.00 | CYP1A1 (0.33) | CYP1A1CYP1A2CYP1B1CSNK2A2CSNK2B | |
| SCHEMBL21801144 | 0.95 | CYP1A1 (0.33) | CYP1A1CYP1A2CYP1B1CSNK2A2CSNK2B | |
| SCHEMBL21801055 | 0.92 | FFAR4 (0.36) | CYP1A1CYP1A2CYP1B1CSNK2A2CSNK2B | |
| SCHEMBL21801105 | 0.88 | CSNK2A2 (0.41) | CYP1A1CYP1A2CYP1B1CSNK2A2CSNK2B | |
| SCHEMBL21801097 | 0.88 | MAOB (0.31) | CYP1A1CYP1A2CYP1B1CSNK2A2CSNK2B | |
| SCHEMBL21886755 | 0.86 | FFAR4 (0.32) | CSNK2A2CSNK2BCSNK2A1FFAR4FFAR1 | |
| SCHEMBL21801126 | 0.82 | MAOB (0.42) | CYP1A1CYP1A2CYP1B1CSNK2A2CSNK2B | |
| SCHEMBL21801218 | 0.79 | CSNK2A2 (0.45) | CYP1A1CYP1A2CYP1B1CSNK2A2CSNK2B | |
| SCHEMBL21801185 | 0.75 | MAOB (0.40) | CYP1A1CYP1A2CYP1B1CSNK2A2CSNK2B | |
| SCHEMBL21886767 | 0.74 | CSNK2A2 (0.41) | CYP1A1CYP1A2CYP1B1CSNK2A2CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |