Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801085 | 1.00 | ALDH2 (0.41) | ALDH2MAOAMAOBABCB1ABCG2 | |
| SCHEMBL29180250 | 0.92 | MAOB (0.43) | ALDH2MAOAMAOBABCB1ABCG2 | |
| SCHEMBL21801231 | 0.92 | MAOB (0.43) | ALDH2MAOAMAOBABCB1ABCG2 | |
| SCHEMBL21801269 | 0.91 | ABCG2 (0.42) | ALDH2MAOAMAOBABCB1ABCG2 | |
| SCHEMBL21801083 | 0.90 | CYSLTR1 (0.45) | ALDH2MAOAMAOBABCB1SIGMAR1 | |
| SCHEMBL21801081 | 0.90 | CYSLTR1 (0.45) | ALDH2MAOAMAOBABCB1SIGMAR1 | |
| SCHEMBL21801191 | 0.90 | CYSLTR1 (0.45) | ALDH2MAOAMAOBABCB1SIGMAR1 | |
| SCHEMBL21801239 | 0.89 | ALDH2 (0.41) | ALDH2MAOAMAOBABCB1ABCG2 | |
| SCHEMBL21801214 | 0.89 | CYP3A4 (0.44) | ALDH2MAOAMAOBABCB1ABCG2 | |
| SCHEMBL21801084 | 0.89 | ABCG2 (0.39) | ALDH2MAOAMAOBABCB1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |