Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | MAOB | P27338 | 5/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138843 | 1.00 | MAPT (0.67) | MAPTMAOBCYP2C19MAOACYP2D6 | |
| SCHEMBL5138841 | 1.00 | MAPT (0.67) | MAPTMAOBCYP2C19MAOACYP2D6 | |
| SCHEMBL14692575 | 0.87 | MAOB (0.72) | MAPTMAOBCYP2C19MAOACYP2D6 | |
| SCHEMBL9420986 | 0.87 | MAOB (0.72) | MAPTMAOBCYP2C19MAOACYP2D6 | |
| SCHEMBL5085503 | 0.85 | MAPT (0.64) | MAPTMAOBMAOAABCG2MEN1 | |
| SCHEMBL5085506 | 0.85 | MAPT (0.64) | MAPTMAOBMAOAABCG2MEN1 | |
| SCHEMBL5138124 | 0.83 | MAPT (0.63) | MAPTMAOBCYP2C19MAOAABCG2 | |
| SCHEMBL5138125 | 0.83 | MAPT (0.63) | MAPTMAOBCYP2C19MAOAABCG2 | |
| SCHEMBL30504733 | 0.83 | F3 (0.71) | MAPTMAOBCYP2C19MAOACYP2D6 | |
| SCHEMBL5138954 | 0.83 | KDM4E (0.70) | MAPTMAOBCYP2C19MAOACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |