SCHEMBL30744401

SCHEMBL30744401

NC1CC(Nc2cnc(C(F)(F)F)cn2)C1

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 16/20 0.44
CCNK O75909 1/20 0.39
CDK12 Q9NYV4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21491972 1.00 HCRTR1 (0.44) HCRTR1CCNKCDK12
SCHEMBL21491975 1.00 HCRTR1 (0.44) HCRTR1CCNKCDK12
Hydrochloric Acid SCHEMBL21491930 0.98 HCRTR1 (0.43) HCRTR1CCNKCDK12
Hydrochloric Acid SCHEMBL30744328 0.98 HCRTR1 (0.43) HCRTR1CCNKCDK12
Hydrochloric Acid SCHEMBL21491928 0.98 HCRTR1 (0.43) HCRTR1CCNKCDK12
SCHEMBL21503404 0.89 HCRTR1 (0.44) HCRTR1CCNKCDK12
Hydrochloric Acid SCHEMBL30744538 0.88 HCRTR1 (0.44) HCRTR1CCNKCDK12
Hydrochloric Acid SCHEMBL21492451 0.88 HCRTR1 (0.44) HCRTR1CCNKCDK12
SCHEMBL26703970 0.80 HCRTR1 (0.39) HCRTR1CCNKCDK12
SCHEMBL26703973 0.80 HCRTR1 (0.39) HCRTR1CCNKCDK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112218865-B Pteridinone compounds and uses thereof 沃泰克斯药物股份有限公司 2024-03-12 CN disclosed