SCHEMBL30744883

SCHEMBL30744883

CCOC(=O)c1nc(P(=O)(c2ccccc2)c2ccccc2)c2ccccc2c1C

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.53
MEN1 O00255 4/20 0.53
KDM4E B2RXH2 5/20 0.45
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
POLB P06746 1/20 0.44
ELANE P08246 4/20 0.43
SMN1; SMN2 Q16637 5/20 0.43
ALDH1A1 P00352 3/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 1/20 0.43
TARBP2 Q15633 1/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
NPY1R P25929 1/20 0.41
NPY2R P49146 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
GPR55 Q9Y2T6 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29156685 1.00 KMT2A (0.53) KMT2AMEN1KDM4EMAPK1L3MBTL1
SCHEMBL29156701 0.86 KMT2A (0.50) KMT2AMEN1KDM4EMAPK1L3MBTL1
SCHEMBL30744814 0.86 KMT2A (0.50) KMT2AMEN1KDM4EMAPK1L3MBTL1
SCHEMBL29156670 0.79 KMT2A (0.45) KMT2AMEN1KDM4EL3MBTL1ELANE
SCHEMBL29156719 0.79 MAPT (0.47) KMT2AMEN1KDM4EPOLBELANE
SCHEMBL30744825 0.79 KMT2A (0.44) KMT2AMEN1KDM4EMAPK1L3MBTL1
SCHEMBL29156678 0.79 KMT2A (0.44) KMT2AMEN1KDM4EMAPK1L3MBTL1
SCHEMBL29156720 0.79 GAA (0.46) KMT2AMEN1KDM4EPOLBELANE
SCHEMBL30744897 0.78 KMT2A (0.46) KMT2AMEN1KDM4EMAPK1L3MBTL1
SCHEMBL29156673 0.78 KMT2A (0.46) KMT2AMEN1KDM4EMAPK1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117534705-A Method for synthesizing phosphoryl heterocyclic aromatic hydrocarbon by photocatalysis 中国科学院理化技术研究所 2024-02-09 CN disclosed