Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 7/20 | 0.59 |
| ▸ | BRD4 | O60885 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.52 |
| ▸ | KDM6B | O15054 | 1/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944704 | 1.00 | NR4A2 (0.59) | NR4A2BRD4KDM4EMAP2K1KDM6B | |
| SCHEMBL29302063 | 0.87 | ELANE (0.48) | NR4A2BRD4KDM4EKDM6BKDM5A | |
| SCHEMBL29376883 | 0.84 | ELANE (0.46) | NR4A2BRD4KDM4EKDM6BKDM5A | |
| SCHEMBL17995257 | 0.84 | ELANE (0.46) | NR4A2BRD4KDM4EKDM6BKDM5A | |
| SCHEMBL15077828 | 0.84 | BRD4 (0.56) | BRD4KDM4EKDM6BKDM5AKDM4C | |
| SCHEMBL2012994 | 0.83 | KDM4E (0.60) | BRD4KDM4EKDM6BKDM5AKDM4C | |
| SCHEMBL22559023 | 0.81 | KDM4E (0.50) | BRD4KDM4EKDM6BKDM5AKDM4C | |
| SCHEMBL29302088 | 0.81 | ELANE (0.52) | KDM4EKDM6BKDM5AKDM4CELANE | |
| SCHEMBL2053367 | 0.81 | CNR1 (0.68) | BRD4CNR1CNR2LMNA | |
| SCHEMBL4062044 | 0.80 | KDM4E (0.42) | NR4A2BRD4KDM4EMAP2K1KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |