Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | CD44 | P16070 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944698 | 1.00 | TSHR (0.50) | TSHRADORA1CD44SLC6A2SLC6A4 | |
| SCHEMBL31686161 | 0.89 | TSHR (0.50) | TSHRADORA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL26643886 | 0.89 | TSHR (0.50) | TSHRADORA1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL21496827 | 0.87 | TSHR (0.54) | TSHRALDH1A1HSD17B10CLEC4MCDC25B | |
| Hydrochloric Acid SCHEMBL21496725 | 0.86 | TSHR (0.53) | TSHRALDH1A1HSD17B10CLEC4MCDC25B | |
| SCHEMBL2355554 | 0.84 | CD44 (0.49) | TSHRCD44ALDH1A1HSD17B10 | |
| SCHEMBL29609011 | 0.84 | CD44 (0.49) | TSHRCD44ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL4438179 | 0.83 | CD44 (0.47) | TSHRCD44ALDH1A1HSD17B10 | |
| SCHEMBL7276418 | 0.80 | TSHR (0.56) | TSHRALDH1A1HSD17B10CLEC4MCDC25B | |
| SCHEMBL10642313 | 0.78 | KDM4E (0.45) | TSHRADORA1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |