Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28413725 | 1.00 | RECQL (0.60) | RECQLMAPTRAB9AKMT2AKDM4E | |
| SCHEMBL20963465 | 1.00 | RECQL (0.60) | RECQLMAPTRAB9AKMT2AKDM4E | |
| SCHEMBL25707071 | 1.00 | RECQL (0.60) | RECQLMAPTRAB9AKMT2AKDM4E | |
| SCHEMBL2804346 | 0.88 | MAPT (0.56) | RECQLMAPTRAB9AKMT2AKDM4E | |
| SCHEMBL2804345 | 0.88 | MAPT (0.56) | RECQLMAPTRAB9AKMT2AKDM4E | |
| SCHEMBL2773603 | 0.88 | RECQL (0.56) | RECQLMAPTRAB9AKMT2AKDM4E | |
| SCHEMBL2773601 | 0.88 | RECQL (0.56) | RECQLMAPTRAB9AKMT2AKDM4E | |
| SCHEMBL9968903 | 0.88 | RECQL (0.56) | RECQLMAPTRAB9AKMT2AKDM4E | |
| SCHEMBL30506507 | 0.88 | MAPT (0.56) | RECQLMAPTRAB9AKMT2AKDM4E | |
| SCHEMBL9968908 | 0.88 | MAPT (0.56) | RECQLMAPTRAB9AKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |