Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2326300 | 0.83 | CA12 (0.50) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL3043828 | 0.82 | CA12 (0.61) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL4670546 | 0.81 | CA12 (0.65) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL29151066 | 0.81 | CA1 (0.60) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL29151055 | 0.81 | CA1 (0.60) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL28865338 | 0.80 | CA12 (0.55) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL10459035 | 0.80 | NPC1 (0.51) | CA12CA1CA2CA9RAB9A | |
| SCHEMBL27250762 | 0.80 | CA12 (0.51) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL4114526 | 0.80 | CA12 (0.55) | CA12CA1CA2CA9HRH3 | |
| SCHEMBL15105004 | 0.80 | CA12 (0.59) | CA12CA1CA2CA9HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510470-A | Pyridazinone compounds and application thereof | 暨南大学 | 2024-02-06 | — | — | CN | disclosed |