Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 4/20 | 0.49 |
| ▸ | RARB | P10826 | 3/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 6/20 | 0.43 |
| ▸ | HTR1A | P08908 | 5/20 | 0.43 |
| ▸ | HTR1D | P28221 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20928536 | 1.00 | PTPN11 (0.49) | PTPN11RARBNR5A1TSHRCYP3A4 | |
| SCHEMBL30504180 | 1.00 | PTPN11 (0.49) | PTPN11RARBNR5A1TSHRCYP3A4 | |
| SCHEMBL20928532 | 1.00 | PTPN11 (0.49) | PTPN11RARBNR5A1TSHRCYP3A4 | |
| SCHEMBL25853064 | 0.99 | PTPN11 (0.47) | PTPN11RARBNR5A1TSHRCYP3A4 | |
| SCHEMBL20928533 | 0.96 | PTPN11 (0.47) | PTPN11RARBNR5A1TSHRCYP3A4 | |
| SCHEMBL30504182 | 0.96 | PTPN11 (0.47) | PTPN11RARBNR5A1TSHRCYP3A4 | |
| SCHEMBL20928525 | 0.94 | SYK (0.45) | PTPN11RARBNR5A1CYP3A4CYP2D6 | |
| SCHEMBL30504175 | 0.94 | SYK (0.45) | PTPN11RARBNR5A1CYP3A4CYP2D6 | |
| SCHEMBL20928526 | 0.94 | SYK (0.45) | PTPN11RARBNR5A1CYP3A4CYP2D6 | |
| SCHEMBL30504178 | 0.94 | SYK (0.45) | PTPN11RARBNR5A1CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11891558-B2 | Solid foam comprising mesogenic ligand-functionalized nanoparticles and methods of making and using the same | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-02-06 | — | — | US | disclosed |