SCHEMBL30745276

SCHEMBL30745276

C#CCC(C)(O)CCn1c(=O)n(C)c2ccc(Nc3ccnc(Cl)c3C#N)cc21

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ BCL6 P41182 20/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20569673 1.00 BCL6 (0.81) BCL6
SCHEMBL30745284 0.91 BCL6 (0.85) BCL6
SCHEMBL20569645 0.91 BCL6 (0.85) BCL6
SCHEMBL20569639 0.90 BCL6 (1.00) BCL6
SCHEMBL30904699 0.90 BCL6 (1.00) BCL6
SCHEMBL20569097 0.89 BCL6 (0.81) BCL6
SCHEMBL30745277 0.89 BCL6 (0.81) BCL6
SCHEMBL20569474 0.88 BCL6 (0.84) BCL6
SCHEMBL30745283 0.88 BCL6 (0.84) BCL6
SCHEMBL20569676 0.87 BCL6 (0.84) BCL6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630291-B9 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-05-29 — — EP claimed
EP-3630291-B1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-01-10 — — EP claimed
US-20240417388-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 CANCER RESEARCH TECH LTD (GB) 2024-12-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240417388-A1 BENZIMIDAZOLONE DERIVED INHIBITORS OF BCL6 BCL6, BCL6B, BCL3 BCL6 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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