Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.39 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745471 | 0.92 | MAPT (0.46) | MAOBMAPTMEN1LMNAKMT2A | |
| SCHEMBL30745486 | 0.92 | MAOB (0.45) | MAOBMAPTMEN1LMNAKMT2A | |
| SCHEMBL30745444 | 0.92 | MAOB (0.46) | MAOBMAPTMEN1LMNAKMT2A | |
| SCHEMBL30745480 | 0.90 | MEN1 (0.44) | MAOBMAPTMEN1LMNAKMT2A | |
| SCHEMBL30745439 | 0.88 | MAOB (0.48) | MAOBMAPTMEN1LMNAKMT2A | |
| SCHEMBL30745450 | 0.88 | MAPT (0.43) | MAOBMAPTMEN1LMNAKMT2A | |
| SCHEMBL30745469 | 0.84 | ABCG2 (0.44) | MAOBABCG2ARCXCL12CXCR4 | |
| SCHEMBL30745489 | 0.84 | MAOB (0.47) | MAOBMAPTMEN1LMNAKMT2A | |
| SCHEMBL30745435 | 0.83 | MAOB (0.46) | MAOBMAPTMEN1LMNAKMT2A | |
| SCHEMBL30745496 | 0.82 | MAOB (0.53) | MAOBMAPTMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | disclosed |