Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27011282 | 1.00 | KDM1A (0.51) | KDM1ARCOR1ALDH1A1TSHRKDM4E | |
| SCHEMBL27011325 | 1.00 | KDM1A (0.51) | KDM1ARCOR1ALDH1A1TSHRKDM4E | |
| SCHEMBL30745512 | 1.00 | KDM1A (0.51) | KDM1ARCOR1ALDH1A1TSHRKDM4E | |
| SCHEMBL26140160 | 0.85 | KDM4E (0.54) | KDM1ARCOR1ALDH1A1TSHRKDM4E | |
| SCHEMBL14723747 | 0.79 | NPC1 (0.54) | KDM1ARCOR1ALDH1A1TSHRKDM4E | |
| SCHEMBL29368134 | 0.79 | F2 (0.51) | KDM1ARCOR1ALDH1A1TSHRKDM4E | |
| SCHEMBL16376892 | 0.79 | F2 (0.48) | ALDH1A1TSHRKDM4ELMNAMAPK1 | |
| SCHEMBL10136487 | 0.79 | F2 (0.48) | ALDH1A1TSHRKDM4ELMNAMAPK1 | |
| SCHEMBL31188287 | 0.78 | NPC1 (0.57) | KDM1ARCOR1ALDH1A1TSHRKDM4E | |
| SCHEMBL27006225 | 0.78 | NPC1 (0.50) | KDM1ARCOR1ALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018129-A1 | COMPOUNDS AS PU. 1 INHIBITORS | S-Infinity Pharmaceuticals (CN) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018129-A1 | COMPOUNDS AS PU. 1 INHIBITORS | FLI1, MCL1, SP1 | KDM1A 455/4885RCOR1 175/4885ALDH1A1 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.